David Koffler - Semantic Scholar
Henry G. Kunkel28
Vincent Agnello15
G E Biesecker13
Ronald I. Carr12
Fiorenzo Paronetto10
22Henry G. Kunkel
20George J. Kaloyanides
20John E. Lewy
20John B. Winfield
18Vincent Agnello
Avidity of anti-DNA antibodies in serum and IgG glomerular eluates from patients with systemic lupus erythematosus. Association of high avidity antinative DNA antibody with glomerulonephritis.
John B. Winfield, Isidore Faiferman, David Koffler
Significant differences in both specificity and avidity of anti-DNA antibodies were observed in the sera of groups of patients with active systemic lupus erythematosus glomerulonephritis, active… (More)
Intrathecal IgG synthesis and blood-brain barrier impairment in patients with systemic lupus erythematosus and central nervous system dysfunction.
John B. Winfield, Michael Shaw, Lawrence M. Silverman, Robert A. Eisenberg, H. A. Wilson, David Koffler
Paired serum and cerebrospinal fluid specimens from 19 patients with SLE and central nervous system dysfunction were studied with respect to cerebrospinal fluid IgG index (a measure of intrathecal… (More)
G E Biesecker, David Koffler
Genetically related susceptibility for experimental autoimmune myasthenia gravis was investigated in nine inbred strains of rats immunized with heterologous acetylcholine (AChR) from Torpedo… (More)
Systemic lupus erythematosus: prototype of immune complex nephritis in man.
David Koffler, Vincent Agnello, R. Thoburn, Henry G. Kunkel
Immunological Studies concerning the Nephritis of Systemic Lupus Erythematosus
David Koffler, Peter H. Schur, Henry G. Kunkel
Antibodies were eluted from the isolated glomeruli prepared from the kidneys of 10 patients with the nephritis of systemic lupus erythematosus. Antibodies reacting primarily with buffer extracts of… (More)
Renal localization of the membrane attack complex in systemic lupus erythematosus nephritis
G E Biesecker, Stephen M. Katz, David Koffler
The membrane attack complex (MAC) of the complement system was localized in both glomeruli and peritubular regions of 22 kidneys manifesting systemic lupus erythematosus (SLE) nephritis. A similar… (More)
Immune complex disease in experimental animals and man.
Charles G. Cochrane, David Koffler
C1q PRECIPITINS IN THE SERA OF PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS AND OTHER HYPOCOMPLEMENTEMIC STATES: CHARACTERIZATION OF HIGH AND LOW MOLECULAR WEIGHT TYPES
Vincent Agnello, David Koffler, J. W. Eisenberg, Robert J. Winchester, Henry G. Kunkel
Precipitin reactions of C1q in gel diffusion proved useful in detecting unknown complexes containing gamma-globulin in the sera of patients with SLE. Using this method low molecular weight C1q… (More)
Interictal spiking increases after seizures but does not after decrease in medication.
Jean Gotman, David Koffler
In patients with focal epilepsy, EEG spike rate fluctuates considerably over time. We had previously shown that seizure occurrence played an important role in these fluctuations. We undertook this… (More)
David Koffler, Richard Carr, Vincent Agnello, R. Thoburn, Henry G. Kunkel
The specificities of anti-polynucleotide antibodies found in human sera were studied using several immunological procedures. Anti-native DNA (NDNA) antibodies and certain anti-double-stranded RNA… (More)
David Koffler - Semantic Scholar
Henry G. Kunkel28
Vincent Agnello15
G E Biesecker13
Ronald I. Carr12
Fiorenzo Paronetto10
22Henry G. Kunkel
20George J. Kaloyanides
20John E. Lewy
20John B. Winfield
18Vincent Agnello
Avidity of anti-DNA antibodies in serum and IgG glomerular eluates from patients with systemic lupus erythematosus. Association of high avidity antinative DNA antibody with glomerulonephritis.
John B. Winfield, Isidore Faiferman, David Koffler
Significant differences in both specificity and avidity of anti-DNA antibodies were observed in the sera of groups of patients with active systemic lupus erythematosus glomerulonephritis, active… (More)
Intrathecal IgG synthesis and blood-brain barrier impairment in patients with systemic lupus erythematosus and central nervous system dysfunction.
John B. Winfield, Michael Shaw, Lawrence M. Silverman, Robert A. Eisenberg, H. A. Wilson, David Koffler
Paired serum and cerebrospinal fluid specimens from 19 patients with SLE and central nervous system dysfunction were studied with respect to cerebrospinal fluid IgG index (a measure of intrathecal… (More)
G E Biesecker, David Koffler
Genetically related susceptibility for experimental autoimmune myasthenia gravis was investigated in nine inbred strains of rats immunized with heterologous acetylcholine (AChR) from Torpedo… (More)
Systemic lupus erythematosus: prototype of immune complex nephritis in man.
David Koffler, Vincent Agnello, R. Thoburn, Henry G. Kunkel
Immunological Studies concerning the Nephritis of Systemic Lupus Erythematosus
David Koffler, Peter H. Schur, Henry G. Kunkel
Antibodies were eluted from the isolated
 glomeruli prepared from the kidneys of 10 patients with the nephritis of systemic lupus erythematosus. Antibodies reacting primarily with buffer extracts of… (More)
Renal localization of the membrane attack complex in systemic lupus erythematosus nephritis
G E Biesecker, Stephen M. Katz, David Koffler
The membrane attack complex (MAC) of the complement system was localized in both glomeruli and peritubular regions of 22 kidneys manifesting systemic lupus erythematosus (SLE) nephritis. A similar… (More)
Immune complex disease in experimental animals and man.
Charles G. Cochrane, David Koffler
C1q PRECIPITINS IN THE SERA OF PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS AND OTHER HYPOCOMPLEMENTEMIC STATES: CHARACTERIZATION OF HIGH AND LOW MOLECULAR WEIGHT TYPES
Vincent Agnello, David Koffler, J. W. Eisenberg, Robert J. Winchester, Henry G. Kunkel
Precipitin reactions of C1q in gel diffusion proved useful in detecting unknown complexes containing gamma-globulin in the sera of patients with SLE. Using this method low molecular weight C1q… (More)
Interictal spiking increases after seizures but does not after decrease in medication.
Jean Gotman, David Koffler
In patients with focal epilepsy, EEG spike rate fluctuates considerably over time. We had previously shown that seizure occurrence played an important role in these fluctuations. We undertook this… (More)
David Koffler, Richard Carr, Vincent Agnello, R. Thoburn, Henry G. Kunkel
The specificities of anti-polynucleotide antibodies found in human sera were studied using several immunological procedures. Anti-native DNA (NDNA) antibodies and certain anti-double-stranded RNA… (More)